Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | IL1B | P01584 | 7/20 | 0.43 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30375062 | 1.00 | NLRP3 (0.68) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL26438939 | 1.00 | NLRP3 (0.68) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL26093704 | 1.00 | NLRP3 (0.68) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL26093286 | 0.93 | NLRP3 (0.68) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL26435889 | 0.93 | NLRP3 (0.68) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL30374849 | 0.93 | NLRP3 (0.68) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL26437103 | 0.88 | NLRP3 (0.54) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL24855438 | 0.87 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL24855752 | 0.87 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 | |
| SCHEMBL30181078 | 0.87 | NLRP3 (0.74) | NLRP3KCNH2IL1BTNFCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |