SCHEMBL26435756

SCHEMBL26435756

Cc1c(F)cc(OCC2OCC(C)CO2)cc1F

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.33
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HIF1A Q16665 2/20 0.33
CYP3A4 P08684 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
KDM1A O60341 1/20 0.31
MAPT P10636 2/20 0.30
HPGD P15428 2/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30
PPARG P37231 1/20 0.30
LMNA P02545 1/20 0.30
MAOA P21397 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15985666 0.85 GRM5 (0.33) TP53TSHRALDH1A1HIF1ACYP3A4
SCHEMBL17548005 0.81 ALDH1A1 (0.37) TP53TSHRALDH1A1HIF1ACYP3A4
SCHEMBL15985665 0.80 ALDH1A1 (0.53) TP53TSHRALDH1A1HIF1ACYP3A4
SCHEMBL17548060 0.74 BACE1 (0.35) HPGD
SCHEMBL17548007 0.74 PARP10 (0.40) HPGD
SCHEMBL17548059 0.74 TP53 (0.34) TP53TSHRALDH1A1HIF1ACYP3A4
SCHEMBL18531588 0.73 SLC6A2 (0.33) SLC6A2
SCHEMBL17548069 0.73 ALDH1A1 (0.31) TP53TSHRALDH1A1HIF1ACYP3A4
SCHEMBL15985671 0.71 GRM5 (0.47) ALDH1A1SMN1; SMN2TDP1MAPTHPGD
SCHEMBL14444655 0.71 PARP10 (0.38) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023232753-A1 FERROELECTRIC SMECTIC LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-12-07 WO disclosed
WO-2023232754-A1 FERROELECTRIC NEMATIC LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-12-07 WO disclosed
WO-2023066826-A1 ELECTRO-MECHANICAL CONVERTERS USING FERROELECTRIC NEMATIC MATERIAL MERCK PATENT GMBH (DE) 2023-04-27 WO disclosed