Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LATS1 | O95835 | 2/20 | 0.35 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437123 | 0.88 | NLRP3 (0.41) | NLRP3KCNH2KDM4EKMT2ALATS1 | |
| SCHEMBL26437763 | 0.87 | NLRP3 (0.42) | NLRP3KCNH2KDM4EHSD17B10LATS1 | |
| SCHEMBL26437757 | 0.86 | NLRP3 (0.41) | NLRP3KCNH2LATS1LATS2CHRM1 | |
| SCHEMBL26435303 | 0.85 | NLRP3 (0.52) | NLRP3KCNH2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL26436323 | 0.85 | NLRP3 (0.57) | NLRP3KCNH2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL26093175 | 0.85 | NLRP3 (0.57) | NLRP3KCNH2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL26437579 | 0.84 | NLRP3 (0.55) | NLRP3KCNH2KDM4EKMT2ALATS1 | |
| SCHEMBL26435052 | 0.82 | NLRP3 (0.47) | NLRP3KCNH2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL26437137 | 0.81 | NLRP3 (0.51) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL26437253 | 0.77 | NLRP3 (0.39) | NLRP3KCNH2KDM4EKMT2AIRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |