Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 16/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 10/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437396 | 0.91 | IL1B (0.54) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL26089492 | 0.89 | IL1B (0.75) | IL1BNLRP3 | |
| SCHEMBL26089483 | 0.89 | IL1B (0.75) | IL1BNLRP3 | |
| SCHEMBL26437719 | 0.86 | IL1B (0.59) | IL1BNLRP3KCNH2 | |
| SCHEMBL26437733 | 0.86 | IL1B (0.57) | IL1BNLRP3 | |
| SCHEMBL26438925 | 0.85 | IL1B (0.64) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL26437740 | 0.85 | IL1B (0.64) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL26437722 | 0.84 | IL1B (0.44) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL26437402 | 0.84 | IL1B (0.56) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL26437749 | 0.84 | IL1B (0.50) | IL1BNLRP3KCNH2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |