Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | IL1B | P01584 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437761 | 0.94 | NLRP3 (0.54) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26093175 | 0.88 | NLRP3 (0.57) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26436323 | 0.88 | NLRP3 (0.57) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26438783 | 0.87 | NLRP3 (0.68) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26437757 | 0.87 | NLRP3 (0.41) | NLRP3KCNH2 | |
| SCHEMBL26437103 | 0.84 | NLRP3 (0.54) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26436537 | 0.83 | NLRP3 (0.54) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL30375511 | 0.81 | NLRP3 (0.55) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26437005 | 0.81 | NLRP3 (0.55) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26090467 | 0.81 | NLRP3 (0.55) | NLRP3KCNH2IL1BTNFHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |