Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PEPD | P12955 | 2/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16620921 | 0.90 | LMNA (0.49) | LMNARAB9ASMN1; SMN2PKMACE | |
| SCHEMBL14113278 | 0.88 | ACE (0.57) | LMNARAB9AACE | |
| SCHEMBL19192852 | 0.87 | SMN1; SMN2 (0.50) | LMNARAB9ASMN1; SMN2PKMACE | |
| SCHEMBL5491765 | 0.87 | LMNA (0.54) | LMNARAB9ASMN1; SMN2PKMACE | |
| SCHEMBL6882664 | 0.87 | LMNA (0.54) | LMNARAB9ASMN1; SMN2PKMACE | |
| SCHEMBL5491755 | 0.87 | LMNA (0.54) | LMNARAB9ASMN1; SMN2PKMACE | |
| SCHEMBL19192922 | 0.86 | LMNA (0.53) | LMNARAB9ASMN1; SMN2PKMACE | |
| SCHEMBL21902736 | 0.86 | LMNA (0.53) | LMNARAB9ASMN1; SMN2PKMACE | |
| SCHEMBL26199184 | 0.86 | LMNA (0.53) | LMNARAB9ASMN1; SMN2PKMACE | |
| SCHEMBL26199256 | 0.86 | LMNA (0.53) | LMNARAB9ASMN1; SMN2PKMACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068376-A1 | PHARMACEUTICAL COMPOSITION HAVING ANTI-CANCER IMMUNOSTIMULATING EFFECT AND/OR IMMUNE CHECKPOINT INHIBITION POTENTIATING EFFECT | 国立大学法人九州大学 | 2023-04-27 | — | — | WO | disclosed |