Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | QPCT | Q16769 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437835 | 0.89 | HRH3 (0.47) | HRH3QPCTF10AOC3PIK3C3 | |
| SCHEMBL26438121 | 0.89 | HRH3 (0.41) | HRH3QPCTF10AOC3PIK3C3 | |
| SCHEMBL26437555 | 0.83 | HRH3 (0.45) | HRH3QPCTF10AOC3PIK3C3 | |
| SCHEMBL26438237 | 0.82 | HRH3 (0.43) | HRH3QPCTF10AOC3PIK3C3 | |
| SCHEMBL26437932 | 0.82 | HRH3 (0.40) | HRH3QPCTF10AOC3PIK3C3 | |
| SCHEMBL26437954 | 0.77 | HRH3 (0.42) | HRH3QPCTF10AOC3PIK3C3 | |
| SCHEMBL34464680 | 0.77 | HRH3 (0.42) | HRH3QPCTAOC3PIK3C3SUV39H2 | |
| SCHEMBL26438814 | 0.77 | HRH3 (0.45) | HRH3QPCTF10AOC3PIK3C3 | |
| SCHEMBL26437457 | 0.75 | HRH3 (0.49) | HRH3QPCTF10AOC3PIK3C3 | |
| SCHEMBL13336404 | 0.75 | HRH3 (0.49) | HRH3QPCTF10AOC3PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066204-A1 | SIK INHIBITOR, COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2023-04-27 | — | — | WO | disclosed |