Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | SUV39H2 | Q9H5I1 | 6/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437992 | 0.89 | HRH3 (0.42) | HRH3SUV39H2PIK3C3F10AOC3 | |
| SCHEMBL26438297 | 0.85 | HRH3 (0.47) | HRH3SUV39H2QPCTPDE10A | |
| SCHEMBL26437436 | 0.82 | HRH3 (0.49) | HRH3SUV39H2PIK3C3F10AOC3 | |
| SCHEMBL26437457 | 0.82 | HRH3 (0.49) | HRH3SUV39H2PIK3C3F10AOC3 | |
| SCHEMBL13336404 | 0.82 | HRH3 (0.49) | HRH3SUV39H2PIK3C3F10AOC3 | |
| SCHEMBL26438121 | 0.81 | HRH3 (0.41) | HRH3SUV39H2PIK3C3F10AOC3 | |
| SCHEMBL26437646 | 0.79 | HRH3 (0.54) | HRH3SUV39H2PIK3C3F10AOC3 | |
| SCHEMBL26437508 | 0.79 | SYK (0.45) | HRH3SUV39H2PIK3C3F10AOC3 | |
| SCHEMBL26437360 | 0.76 | HRH3 (0.54) | HRH3SUV39H2PIK3C3QPCT | |
| SCHEMBL26437555 | 0.76 | HRH3 (0.45) | HRH3SUV39H2PIK3C3F10AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066204-A1 | SIK INHIBITOR, COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2023-04-27 | — | — | WO | disclosed |