⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644968 | 0.78 | — | — | |
| SCHEMBL10515983 | 0.75 | ATM (0.40) | — | |
| SCHEMBL9837341 | 0.70 | — | — | |
| SCHEMBL1680479 | 0.69 | — | — | |
| SCHEMBL1680480 | 0.69 | — | — | |
| SCHEMBL461534 | 0.69 | — | — | |
| SCHEMBL1680475 | 0.69 | — | — | |
| SCHEMBL269126 | 0.69 | — | — | |
| SCHEMBL577440 | 0.69 | — | — | |
| SCHEMBL29857 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399608-B1 | FLUOXETINE, PAROXETINE OR SERTRALINE WITH 1,2,4-TRIAZOLO (4,3-B)PYRIDAZINE DERIVATIVE; NONSEDATING ANXIOLYTIC MODULATOR OF BENZODIAZEPINE BINDING SITE OF GAMMA AMINO-BUTYRIC ACID RECEPTOR; CENTRAL NERVOUS SYSTEM | MERCK SHARP & DOHME LTD. (GB) | 2002-06-04 | — | — | US | claimed |
| EP-0713488-B1 | [1,3,4]TRIAZOLO [1,5-AL]PYRIDINES USED AS INTERMEDIATE PRODUCTS FOR THE SYNTHESIS OF DYES | BASF AG (DE) | 1997-10-15 | — | — | EP | claimed |
| EP-0291852-A1 | Triazole compounds, process for their preparation and method for plant growth regulation | BASF Aktiengesellschaft (DE) | 1988-11-23 | — | — | EP | claimed |
| CN-101983200-B | Infrared absorbing compound and fine particles containing the same | FUJI PHOTO FILM CO LTD | 2013-07-24 | — | — | CN | disclosed |
| CN-101983200-A | Infrared absorbing compound and fine particles containing the same | FUJIFILM CORP | 2011-03-02 | — | — | CN | disclosed |
| EP-2064209-A1 | PYRROLE DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008020222-A1 | PYRROLE DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2008-02-21 | — | — | WO | disclosed |
| EP-1121361-B1 | PYRAZOLO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME (GB) | 2007-08-29 | — | — | EP | disclosed |
| US-6872720-B2 | Pyrazolo-triazine derivatives as ligands for gaba receptors | MERCK SHARP & DOHME LTD. | 2005-03-29 | — | — | US | disclosed |
| US-6730676-B2 | CENTRAL NERVOUS SYSTEM DISORDERS; COGNITION ACTIVATORS | MERCK SHARP & DOHME LTD. | 2004-05-04 | — | — | US | disclosed |
| US-6730681-B2 | ANXIOLYTIC AGENTS AND ANTICONVULSANTS | MERCK SHARP & DOHME LTD. | 2004-05-04 | — | — | US | disclosed |
| EP-0713488-B1 | [1,3,4]TRIAZOLO [1,5-AL]PYRIDINES USED AS INTERMEDIATE PRODUCTS FOR THE SYNTHESIS OF DYES | BASF AG (DE) | 1997-10-15 | — | — | EP | disclosed |
| EP-0235301-B1 | PYRIDOPYRIMIDINE NUCLEOTIDE DERIVATIVES | TEIJIN LIMITED (JP) | 1992-07-22 | — | — | EP | disclosed |
| EP-0421267-A2 | Synergetic triazole compounds | BASF Aktiengesellschaft (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4988818-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4969950-A | Triazole compounds and methods for regulating plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1990-11-13 | — | — | US | disclosed |
| US-4965350-A | FLUORESCENT DETECTORS | TEIJIN LIMITED (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0291852-A1 | Triazole compounds, process for their preparation and method for plant growth regulation | BASF Aktiengesellschaft (DE) | 1988-11-23 | — | — | EP | disclosed |
| EP-0235301-A1 | PYRIDOPYRIMIDINE NUCLEOTIDE DERIVATIVES | TEIJIN LIMITED (JP) | 1987-09-09 | — | — | EP | disclosed |
| US-4080502-A | 2,4-Dioxo-hexahydro-1,3,5-triazines | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |