Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | IL1B | P01584 | 3/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26436986 | 1.00 | NLRP3 (0.52) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26438488 | 0.93 | NLRP3 (0.52) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26436983 | 0.93 | NLRP3 (0.52) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL31072355 | 0.93 | NLRP3 (0.52) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26436782 | 0.85 | NLRP3 (0.56) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL30375345 | 0.85 | NLRP3 (0.56) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26438480 | 0.85 | NLRP3 (0.56) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26437007 | 0.85 | NLRP3 (0.55) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26438486 | 0.85 | NLRP3 (0.55) | NLRP3KCNH2IL1BTNFHCRTR1 | |
| SCHEMBL26437564 | 0.81 | NLRP3 (0.72) | NLRP3KCNH2IL1BTNFHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |