Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 18/20 | 0.66 |
| ▸ | ALOX5AP | P20292 | 17/20 | 0.66 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15917145 | 0.81 | FEN1 (1.00) | FEN1ALOX5AP | |
| SCHEMBL14988677 | 0.77 | KDM1A (0.59) | FEN1ALOX5APKDM1AIDO1 | |
| SCHEMBL28107573 | 0.77 | FEN1 (0.66) | FEN1ALOX5AP | |
| SCHEMBL2030727 | 0.77 | FEN1 (0.66) | FEN1ALOX5APIDO1 | |
| SCHEMBL3010313 | 0.77 | FEN1 (0.77) | FEN1ALOX5AP | |
| SCHEMBL15916606 | 0.75 | ALOX5AP (0.78) | FEN1ALOX5AP | |
| SCHEMBL27761291 | 0.74 | FEN1 (0.55) | FEN1ALOX5APKDM1A | |
| SCHEMBL20627407 | 0.74 | FEN1 (0.57) | FEN1ALOX5AP | |
| SCHEMBL29518695 | 0.74 | IDO1 (0.43) | FEN1ALOX5APKDM1AIDO1 | |
| SCHEMBL10005680 | 0.74 | ATR (0.49) | FEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107857342-A | It is a kind of with the electrolyzing sewage pond of solar silicon plate and its method of work | 徐州工程学院 | 2018-03-30 | — | — | CN | claimed |
| CN-107857342-A | It is a kind of with the electrolyzing sewage pond of solar silicon plate and its method of work | 徐州工程学院 | 2018-03-30 | — | — | CN | disclosed |
| EP-1572670-B1 | 5-SUBSTITUTED-PYRAZINE OR -PYRIDINE GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2007-08-22 | — | — | EP | disclosed |
| US-7132425-B2 | 5-substituted-six-membered heteroaromatic glucokinase activators | HOFFMANN-LA ROCHE INC. (US) | 2006-11-07 | — | — | US | disclosed |
| EP-1572670-A1 | 5-SUBSTITUTED-PYRAZINE OR -PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| US-20040147748-A1 | 5-Substituted-six-membered heteroaromatic glucokinase activators | CHEN SHAOQING (US) | 2004-07-29 | — | — | US | disclosed |
| WO-2004052869-A1 | 5-SUBSTITUTED-PYRAZINE OR PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147748-A1 | 5-Substituted-six-membered heteroaromatic glucokinase activators | GCK, GCKR, GALK1 | FEN1 4364/4885ALOX5AP 3219/4885KDM1A 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.