Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | ATR | Q13535 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2643887 | 0.74 | FEN1 (0.66) | IDO1KDM1AALOX5APFEN1 | |
| SCHEMBL28458373 | 0.74 | HTR2B (0.49) | IDO1ATRKDM1AALOX5APFEN1 | |
| SCHEMBL14988372 | 0.71 | CCR6 (0.48) | KDM1AALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL2070382 | 0.70 | LDHA (0.64) | IDO1KDM1ACYP19A1ALDH1A1HPGD | |
| SCHEMBL5934219 | 0.69 | ALPL (0.49) | IDO1ATRALDH1A1HPGDHSD17B10 | |
| SCHEMBL11886380 | 0.68 | IDO1 (0.47) | IDO1KDM1AALOX5APFEN1CYP19A1 | |
| SCHEMBL31681935 | 0.68 | IDO1 (0.47) | IDO1KDM1AALOX5APFEN1CYP19A1 | |
| Acetic Acid SCHEMBL7239234 | 0.68 | ALOX5AP (0.45) | IDO1KDM1AALOX5APFEN1ALDH1A1 | |
| SCHEMBL13818451 | 0.67 | NPC1 (0.62) | IDO1KDM1ACYP19A1ALDH1A1HPGD | |
| SCHEMBL21661952 | 0.67 | KDM1A (0.51) | IDO1KDM1AALOX5APFEN1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033362-A1 | SYNTHETIC METHOD AND APPLICATION OF 2-HYDROXYPHENYL-5-PYRAZINYL KETONE | INTELLIGENT MANUFACTURING INSTITUTE OF HEFEI UNIVERSITY TECHNOLOGY (CN) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033362-A1 | SYNTHETIC METHOD AND APPLICATION OF 2-HYDROXYPHENYL-5-PYRAZINYL KETONE | PAH, HRH2, HRH4 | IDO1 376/4885ATR 721/4885KDM1A 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.