SCHEMBL264430

SCHEMBL264430

CCCCCCCCCC=C[SiH3]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.54
TRPV1 Q8NER1 1/20 0.54
TSHR P16473 2/20 0.48
TERT O14746 3/20 0.46
PTPN1 P18031 3/20 0.46
CYP1A2 P05177 2/20 0.46
MAPT P10636 2/20 0.46
CYP2C19 P33261 2/20 0.46
BLM P54132 2/20 0.46
HSD17B10 Q99714 2/20 0.46
FABP4 P15090 2/20 0.46
PPARG P37231 2/20 0.46
KMT2A Q03164 2/20 0.46
PPARD Q03181 2/20 0.46
PPARA Q07869 2/20 0.46
GMNN O75496 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1556993 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL28693077 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL28260903 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL9797631 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL5410002 1.00
SCHEMBL28517128 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL12814365 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL4517095 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTPTPN1
SCHEMBL5409999 1.00
SCHEMBL7042251 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105229016-A By the saturated and unsaturated silahydrocarbons of the olefinic silane of iron and the catalysis of cobalt pyridine diimine MOMENTIVE PERFORMANCE MAT INC 2016-01-06 CN claimed
CN-105229016-B Pass through the saturation and unsaturation silahydrocarbons of the olefinic silane that iron and cobalt pyridine diimine are catalyzed 莫门蒂夫性能材料股份有限公司 2018-11-27 CN disclosed
CN-105229016-A By the saturated and unsaturated silahydrocarbons of the olefinic silane of iron and the catalysis of cobalt pyridine diimine MOMENTIVE PERFORMANCE MAT INC 2016-01-06 CN disclosed
US-8753811-B2 Method for making populations of defined nucleic acid molecules COLD SPRING HARBOR LABORATORY (US) 2014-06-17 US disclosed
EP-2688917-A2 HYDROSILYATION OF VINYL MACROMERS WITH METALLOCENES Exxonmobil Chemical Patents Inc. (US) 2014-01-29 EP disclosed
WO-2012134726-A2 HYDROSILYATION OF VINYL MACROMERS WITH METALLOCENES EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-10-04 WO disclosed
US-20120149602-A1 METHOD FOR MAKING POPULATIONS OF DEFINED NUCLEIC ACID MOLECULES COLD SPRING HARBOR LABORATORY 2012-06-14 US disclosed
US-8133670-B2 Method for making populations of defined nucleic acid molecules COLD SPRING HARBOR LABORATORY (US) 2012-03-13 US disclosed
EP-1288664-B1 Methods for generating ligand arrays AGILENT TECHNOLOGIES INC (US) 2007-03-07 EP disclosed
WO-2005001134-A1 METHOD FOR MAKING LIBRARY OF DEFINED NUCLEIC ACID MOLECULES ROSETTA INPHARMATICS LLC (US) 2005-01-06 WO disclosed
US-20040259146-A1 making libraries; synthesizing nucleic acids of predetermined sequence on a substrate and localizing each to a defined area of a substrate, then introducing harvested nucleic acid molecules into vectors; individual synthesis of nucleic acid molecules is costly, inefficient ROSETTA INPHARMATICS LLC 2004-12-23 US disclosed
US-20030044798-A1 Methods for generating ligand arrays via deposition of ligands onto olefin displaying substrates, and arrays produced thereby AGILENT TECHNOLOGIES, INC. 2003-03-06 US disclosed
EP-1288664-A1 Methods for generating ligand arrays Agilent Technologies, Inc. (US) 2003-03-05 EP disclosed