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SCHEMBL26443146

SCHEMBL26443146

Cc1ccc(N(c2ccc(-c3ccc4c(c3)C(C)(C)c3cc(C)ccc3-4)cc2)c2ccc(-c3ccc4c(c3)c3ccccc3n4-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TSPO P30536 1/20 0.36
▸ PDK2 Q15119 1/20 0.33
▸ AKR1C4 P17516 1/20 0.32
▸ AKR1C3 P42330 1/20 0.32
▸ AKR1C2 P52895 1/20 0.32
▸ AKR1C1 Q04828 1/20 0.32
▸ PGR P06401 1/20 0.31
▸ NPY5R Q15761 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26443211 0.95 TSPO (0.35) TSPOPDK2AKR1C4AKR1C3AKR1C2
SCHEMBL26443112 0.95 TSPO (0.35) TSPOPDK2AKR1C4AKR1C3AKR1C2
SCHEMBL26443218 0.95 TSPO (0.35) TSPOPDK2AKR1C4AKR1C3AKR1C2
SCHEMBL26443203 0.94 TSPO (0.36) TSPOPDK2AKR1C4AKR1C3AKR1C2
SCHEMBL26443178 0.94 TSPO (0.36) TSPOPDK2AKR1C4AKR1C3AKR1C2
SCHEMBL26443147 0.94 PDK2 (0.33) TSPOPDK2AKR1C4AKR1C3AKR1C2
SCHEMBL26443184 0.94 TSPO (0.37) TSPOPDK2AKR1C4AKR1C3AKR1C2
SCHEMBL26443163 0.94 TSPO (0.37) TSPOPDK2AKR1C4AKR1C3AKR1C2
SCHEMBL26443204 0.93 TSPO (0.34) TSPOPDK2PGR
SCHEMBL26443180 0.93 TSPO (0.34) TSPOPDK2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230126748-A1 POLYMER, A COMPOSITION, AND AN ELECTROLUMINESCENT DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-04-27 — — US disclosed
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