Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | AR | P10275 | 4/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443269 | 0.83 | CA1 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4628852 | 0.83 | EPHX2 (0.46) | EPHX2ARPGRCYP11B1CYP11B2 | |
| SCHEMBL16186298 | 0.82 | EPHX2 (0.43) | EPHX2ARPGRCYP11B1CYP11B2 | |
| SCHEMBL2900162 | 0.79 | EPHX2 (0.44) | EPHX2ARPGRCYP11B1CYP11B2 | |
| SCHEMBL29775318 | 0.79 | CA12 (0.56) | EPHX2ARPGRCA12CA1 | |
| SCHEMBL12422332 | 0.79 | CA12 (0.56) | EPHX2ARPGRCA12CA1 | |
| SCHEMBL756255 | 0.79 | PTPN7 (0.50) | EPHX2ARPGRCYP11B1CYP11B2 | |
| SCHEMBL29775423 | 0.79 | PTPN7 (0.50) | EPHX2ARPGRCYP11B1CYP11B2 | |
| SCHEMBL14949902 | 0.79 | NQO1 (0.46) | AR | |
| SCHEMBL12478621 | 0.78 | EPHX2 (0.43) | EPHX2ARPGRCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4174069-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2023-05-03 | — | — | EP | disclosed |