Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8225493 | 0.90 | CA1 (0.48) | EPHX2CYP11B1CYP11B2ARPGR | |
| SCHEMBL22140448 | 0.83 | EPHX2 (0.43) | EPHX2CYP11B1CYP11B2ARPGR | |
| SCHEMBL2900162 | 0.83 | EPHX2 (0.44) | EPHX2CYP11B1CYP11B2ARPGR | |
| SCHEMBL21446957 | 0.83 | CYP11B1 (0.44) | EPHX2CYP11B1CYP11B2ARPGR | |
| SCHEMBL29775318 | 0.83 | CA12 (0.56) | EPHX2ARPGRCA12CA1 | |
| SCHEMBL7909509 | 0.83 | CA12 (0.56) | CYP11B1CYP11B2ARPGRCA12 | |
| SCHEMBL756255 | 0.83 | PTPN7 (0.50) | EPHX2CYP11B1CYP11B2ARPGR | |
| SCHEMBL15305003 | 0.83 | CYP11B2 (0.59) | EPHX2CYP11B1CYP11B2ARPGR | |
| SCHEMBL31193485 | 0.83 | CA12 (0.56) | CYP11B1CYP11B2ARPGRCA12 | |
| SCHEMBL29775423 | 0.83 | PTPN7 (0.50) | EPHX2CYP11B1CYP11B2ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917239-A1 | FLUOROPROSTAGLANDINS NITRODERIVATIVES | Pfizer, Inc. (US) | 2008-05-07 | — | — | EP | claimed |
| WO-2007000642-A1 | FLUOROPROSTAGLANDINS NITRODERIVATIVES | PFIZER INC. (US) | 2007-01-04 | — | — | WO | claimed |
| EP-1917239-A1 | FLUOROPROSTAGLANDINS NITRODERIVATIVES | Pfizer, Inc. (US) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007000642-A1 | FLUOROPROSTAGLANDINS NITRODERIVATIVES | PFIZER INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| EP-0930296-B2 | FLUORINATED PROSTAGLANDIN DERIVATIVES AND MEDICINES | ASAHI GLASS CO LTD (JP) | 2005-11-02 | — | — | EP | disclosed |
| EP-0850926-B1 | Difluoroprostaglandin derivatives and their use | ASAHI GLASS CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| EP-0930296-B1 | FLUORINATED PROSTAGLANDIN DERIVATIVES AND MEDICINES | ASAHI GLASS CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-5985920-A | COMPOUNDS FOR TREATMENT OF VISION DEFECTS SUCH AS GLAUCOMA | ASAHI GLASS COMPANY LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0930296-A1 | FLUORINATED PROSTAGLANDIN DERIVATIVES AND MEDICINES | ASAHI GLASS COMPANY LTD. (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5886035-A | PREVENTIVE AND THERAPEUTICAL MEDICINE FOR EYE DISEASE | ASAHI GLASS COMPANY LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0850926-A2 | Difluoroprostaglandin derivatives and their use | ASAHI GLASS COMPANY LTD. (JP) | 1998-07-01 | — | — | EP | disclosed |