SCHEMBL26444793

SCHEMBL26444793

CC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)CN)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ERAP2 Q6P179 5/20 0.61
▸ IL1RN P18510 4/20 0.56
▸ ERAP1 Q9NZ08 3/20 0.56
▸ ERBB2 P04626 1/20 0.54
▸ EDNRA P25101 1/20 0.52
▸ MMP1 P03956 1/20 0.52
▸ CTSB P07858 1/20 0.52
▸ CTSK P43235 1/20 0.52
▸ ECE1 P42892 3/20 0.50
▸ KISS1R Q969F8 3/20 0.50
▸ MAGI3 Q5TCQ9 1/20 0.50
▸ MMP2 P08253 2/20 0.49
▸ MMP9 P14780 2/20 0.49
▸ MMP8 P22894 2/20 0.49
▸ GHSR Q92847 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31211772 0.91 ERAP2 (0.62) ERAP2IL1RNERAP1ERBB2EDNRA
SCHEMBL30026081 0.88 ERAP2 (0.59) ERAP2IL1RNERAP1ERBB2EDNRA
SCHEMBL30512698 0.85 ERBB2 (0.65) ERAP2ERBB2EDNRAKISS1RMAGI3
SCHEMBL29794215 0.84 EDNRA (0.60) ERAP2IL1RNERAP1EDNRAMMP1
SCHEMBL30116697 0.84 ERBB2 (0.64) ERAP2ERBB2KISS1RMAGI3
SCHEMBL31388720 0.83 ERAP2 (0.64) ERAP2IL1RNERAP1EDNRAECE1
SCHEMBL30051096 0.83 ECE1 (0.71) ERAP2IL1RNERAP1ECE1
SCHEMBL31442375 0.82 KISS1R (0.60) ERAP2IL1RNERAP1MMP1CTSB
SCHEMBL19492277 0.82 IL23R (0.66) —
SCHEMBL9822645 0.81 ECE1 (0.68) ERAP2IL1RNERAP1MMP1ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES KLEO PHARMACEUTICALS, INC. 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES CD2BP2, CD2, CD47 ERAP2 2429/4885IL1RN 4402/4885ERAP1 1748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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