SCHEMBL26445663

SCHEMBL26445663

O=C(O)CCCCCCCCCCCSc1ccccc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.60
PTGS2 P35354 1/20 0.59
ALDH1A1 P00352 3/20 0.53
RAB9A P51151 3/20 0.51
POLB P06746 3/20 0.50
LPAR2 Q9HBW0 1/20 0.49
LPAR3 Q9UBY5 1/20 0.49
CYSLTR2 Q9NS75 1/20 0.49
CYSLTR1 Q9Y271 1/20 0.49
HDAC3 O15379 2/20 0.46
HDAC4 P56524 2/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC7 Q8WUI4 2/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC10 Q969S8 2/20 0.46
HDAC11 Q96DB2 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
HDAC9 Q9UKV0 2/20 0.46
HDAC5 Q9UQL6 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6232914 0.92 CYP1A2 (0.65) CYP1A2PTGS2ALDH1A1RAB9APOLB
SCHEMBL6232251 0.92 CYP1A2 (0.65) CYP1A2PTGS2ALDH1A1RAB9APOLB
SCHEMBL6234990 0.92 CYP1A2 (0.65) CYP1A2PTGS2ALDH1A1RAB9APOLB
SCHEMBL6234337 0.92 CYP1A2 (0.65) CYP1A2PTGS2ALDH1A1RAB9APOLB
SCHEMBL6232508 0.90 CYP1A2 (0.67) CYP1A2ALDH1A1RAB9APOLBLPAR2
SCHEMBL8155917 0.88 PTGS2 (0.68) PTGS2ALDH1A1CYSLTR2CYSLTR1HDAC3
SCHEMBL8158286 0.88 PTGS2 (0.68) PTGS2ALDH1A1CYSLTR2CYSLTR1HDAC3
SCHEMBL8155943 0.86 PTGS2 (0.66) PTGS2ALDH1A1CYSLTR2CYSLTR1HDAC3
SCHEMBL8162845 0.86 PTGS2 (0.66) PTGS2ALDH1A1CYSLTR2CYSLTR1HDAC3
SCHEMBL21189320 0.86 CYP1A2 (0.68) CYP1A2ALDH1A1RAB9APOLBLPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023069994-A1 IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-04-27 WO disclosed