SCHEMBL26445925

SCHEMBL26445925

CC[C@@H]1C[C@@H](C)CN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
FABP5 Q01469 3/20 0.40
FABP7 O15540 2/20 0.40
EPHX2 P34913 1/20 0.39
CYP1A2 P05177 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
F10 P00742 1/20 0.35
CASP3 P42574 1/20 0.35
DPP8 Q6V1X1 1/20 0.35
DPP9 Q86TI2 1/20 0.35
POLB P06746 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27415347 1.00 KMT2A (0.43) KMT2AFABP5FABP7EPHX2CYP1A2
SCHEMBL13669346 0.88 KMT2A (0.41) KMT2AFABP5FABP7EPHX2CYP1A2
SCHEMBL5494058 0.83 FABP5 (0.45) KMT2AFABP5FABP7EPHX2CYP1A2
SCHEMBL22648522 0.83 FABP5 (0.45) KMT2AFABP5FABP7EPHX2CYP1A2
SCHEMBL30686147 0.83 FABP5 (0.45) KMT2AFABP5FABP7EPHX2CYP1A2
SCHEMBL20357035 0.83 FABP5 (0.45) KMT2AFABP5FABP7EPHX2CYP1A2
SCHEMBL30896035 0.83 FABP5 (0.45) KMT2AFABP5FABP7EPHX2CYP1A2
SCHEMBL20370186 0.83 FABP5 (0.45) KMT2AFABP5FABP7EPHX2CYP1A2
SCHEMBL26764579 0.83 KMT2A (0.43) KMT2AFABP5FABP7EPHX2CYP1A2
SCHEMBL10118378 0.79 NPC1 (0.45) KMT2AFABP5FABP7TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132756-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE, COMPOSITION AND CONJUGATE COMPRISING DOUBLE-STRANDED OLIGONUCLEOTIDE, PREPARATION METHOD THEREOF AND USE THEREOF Suzhou Ribo Life Science Co., Ltd. (CN) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230132756-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE, COMPOSITION AND CONJUGATE COMPRISING DOUBLE-STRANDED OLIGONUCLEOTIDE, PREPARATION METHOD THEREOF AND USE THEREOF POLN, POLM, DUT KMT2A 2025/4885FABP5 797/4885FABP7 704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.