Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25571332 | 0.98 | SIGMAR1 (0.49) | HRH3SIGMAR1 | |
| SCHEMBL20333472 | 0.92 | HRH3 (0.56) | HRH3SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17525468 | 0.90 | HRH3 (0.52) | HRH3SIGMAR1 | |
| SCHEMBL791611 | 0.88 | SIGMAR1 (0.51) | SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17526223 | 0.87 | SIGMAR1 (0.55) | HRH3SIGMAR1 | |
| SCHEMBL17526227 | 0.87 | SIGMAR1 (0.55) | HRH3SIGMAR1 | |
| SCHEMBL791887 | 0.86 | HRH3 (0.50) | HRH3SIGMAR1 | |
| SCHEMBL19578675 | 0.85 | SIGMAR1 (0.53) | SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20332102 | 0.83 | SIGMAR1 (0.46) | HRH3SIGMAR1 | |
| SCHEMBL14470976 | 0.83 | SIGMAR1 (0.45) | HRH3SIGMAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230134280-A1 | CATALYSTS FOR THE FORMATION OF POLYURETHANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-05-04 | — | — | US | disclosed |