SCHEMBL264495

SCHEMBL264495

[CH2]CC(C)c1cccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
SLC6A4 P31645 1/20 0.44
ADRA2A P08913 3/20 0.42
ADRA2B P18089 3/20 0.42
ADRA2C P18825 3/20 0.42
ADRA1A P35348 2/20 0.42
ADRA1D P25100 1/20 0.42
ADRA1B P35368 1/20 0.42
AOC3 Q16853 1/20 0.42
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
CASR P41180 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7453633 1.00 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL536861 0.85 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL1060489 0.82 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL15211048 0.82 TSHR (0.55) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL2127427 0.82 TSHR (0.55) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL7387513 0.80 ALDH1A1 (0.43) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL3412391 0.80 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL3412393 0.80 CYP1A2 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL3410473 0.80 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL28893602 0.80 HTR2A (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112479875-A Method for preparing alpha-oxo-carboxylic ester by selective oxidation of alpha-hydroxy-carboxylic ester 厦门大学 2021-03-12 CN claimed
CN-1738829-B New 2',5'-oligoadenylic acid analog SANKYO CO 2012-11-28 CN claimed
CN-100554233-C The preparation method of alpha-oxocarbonyl compound KURARAY CO (JP) 2009-10-28 CN claimed
US-20240218233-A1 AQUEOUS GELLABLE COMPOSITION AND PIPELINE PIGS OBTAINED THEREFROM HALLIBURTON ENERGY SERVICES, INC. (US) 2024-07-04 US disclosed
WO-2024137036-A1 AQUEOUS GELLABLE COMPOSITION AND PIPELINE PIGS OBTAINED THEREFROM HALLIBURTON ENERGY SERVICES, INC. (US) 2024-06-27 WO disclosed
US-20240191108-A1 TWO COMPONENT (2K) CURABLE ADHESIVE COMPOSITION HENKEL AG & CO KGAA (DE) 2024-06-13 US disclosed
CN-112368317-B Highly reactive double metal cyanide compounds 汉高股份有限及两合公司 2024-04-02 CN disclosed
US-11883803-B2 Highly active double metal cyanide compounds HENKEL AG & CO. KGAA (DE) 2024-01-30 US disclosed
US-11866547-B2 Method for producing functionalized polyesters HENKEL AG & CO. KGAA (DE) 2024-01-09 US disclosed
CN-117120499-A Two-component (2K) curable adhesive composition 汉高股份有限及两合公司 2023-11-24 CN disclosed
EP-4274865-A1 IMPROVED CR(III)-BASED PASSIVATION FOR ZINC-ALUMINUM COATED STEEL Henkel AG & Co. KGaA (DE) 2023-11-15 EP disclosed
CN-1064273-A The new NGF that has generates the active benzene derivative of promotion SANKYO CO (JP) 1992-09-09 CN disclosed
EP-0501656-A2 New benzene derivatives having (NGF) production-promoting activity Sankyo Company Limited (JP) 1992-09-02 EP disclosed
EP-0498680-A1 New beta-amino-alpha-hydroxycarboxylic acids and their use Sankyo Company Limited (JP) 1992-08-12 EP disclosed
CN-1051178-A New heterogeneous ring compound and preparation method thereof YAMANOUCHI PHARMA CO LTD (JP) 1991-05-08 CN disclosed
EP-0425134-A1 Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-05-02 EP disclosed
US-4987132-A PLATELET ACTIVATING FACTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1991-01-22 US disclosed
CN-1030415-A Saturated heterocycle carboxamide derivatives and its preparation method YAMANOUCHI PHARMA CO LTD (JP) 1989-01-18 CN disclosed
EP-0279681-A2 Saturated heterocyclic carboxamide derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-08-24 EP disclosed
US-4104036-A TO IMPROVE OCTANE RATING ATLANTIC RICHFIELD COMPANY (US) 1978-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11883803-B2 Highly active double metal cyanide compounds CYC1, MCCC2, SCO2 ALDH1A1 3648/4885CYP1A2 858/4885CYP2C9 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.