Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 5/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386838 | 0.83 | BUB1 (0.36) | NOS3NOS1NOS2KCNQ3KCNQ2 | |
| SCHEMBL23453941 | 0.79 | IDO1 (0.31) | — | |
| SCHEMBL11966906 | 0.78 | NOS3 (0.41) | NOS3NOS1NOS2ALDH1A1MAPT | |
| SCHEMBL24595030 | 0.78 | NOS3 (0.41) | NOS3NOS1NOS2GABRPGABRD | |
| SCHEMBL30696909 | 0.78 | NOS3 (0.41) | NOS3NOS1NOS2ALDH1A1MAPT | |
| SCHEMBL13547520 | 0.77 | NOS3 (0.59) | NOS3NOS1NOS2KCNQ3KCNQ2 | |
| SCHEMBL31035889 | 0.75 | NOS3 (0.62) | NOS3NOS1NOS2GABRPGABRD | |
| SCHEMBL18398211 | 0.75 | NOS3 (0.47) | NOS3NOS1NOS2MAPTGABRP | |
| SCHEMBL20457490 | 0.75 | AKR1C3 (0.39) | NOS3NOS1NOS2KCNQ3KCNQ2 | |
| SCHEMBL13990810 | 0.74 | GRIN2D (0.39) | NOS3NOS1NOS2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137956-A1 | ALPHA SUBSTITUTED STAT INHIBITORS AND COMPOSITIONS THEREOF | OXFORD FINANCE LLC | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137956-A1 | ALPHA SUBSTITUTED STAT INHIBITORS AND COMPOSITIONS THEREOF | STAT5A, STAT5B, STAT3 | NOS3 2996/4885NOS1 3432/4885NOS2 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.