Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PPID | Q08752 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26455248 | 0.89 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL6575910 | 0.77 | GAA (0.32) | GAASIGMAR1 | |
| SCHEMBL1841141 | 0.74 | ALDH1A1 (0.45) | GAAALDH1A1MAPK1 | |
| SCHEMBL1841641 | 0.74 | ALDH1A1 (0.45) | GAAALDH1A1MAPK1 | |
| SCHEMBL20217023 | 0.74 | MGAM (0.35) | GAATSHRKMT2A | |
| SCHEMBL4529461 | 0.72 | MIF (0.37) | GAASIGMAR1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL10575305 | 0.72 | MIF (0.37) | GAASIGMAR1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL2299440 | 0.71 | POLB (0.40) | ALDH1A1PPIDTSHRHSD17B10MEN1 | |
| SCHEMBL1139972 | 0.69 | BACE1 (0.36) | MAPK1 | |
| SCHEMBL24673556 | 0.69 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230132377-A9 | OLIGONUCLEOTIDES CONJUGATES COMPRISING 7'-5'-ALPHA-ANOMERIC-BICYCLIC SUGAR NUCLEOSIDES | ALPHA ANOMERIC SAS (FR) | 2023-04-27 | — | — | US | disclosed |