⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14218120 | 0.69 | — | — | |
| SCHEMBL14218127 | 0.63 | — | — | |
| SCHEMBL9945748 | 0.62 | — | — | |
| SCHEMBL13265156 | 0.62 | INMT (0.30) | — | |
| SCHEMBL14140958 | 0.60 | — | — | |
| SCHEMBL17055584 | 0.58 | INMT (0.32) | — | |
| SCHEMBL23868277 | 0.56 | — | — | |
| SCHEMBL13238885 | 0.56 | INMT (0.30) | — | |
| SCHEMBL3043 | 0.56 | — | — | |
| SCHEMBL717518 | 0.56 | BRD4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075766-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023076352-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-04 | — | — | WO | disclosed |