SCHEMBL26458261

SCHEMBL26458261

O=C(O)CCCCOc1c(-c2csc(N3CCOCC3)n2)ccc(F)c1F

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 16/20 0.67
▸ RAB9A P51151 4/20 0.44
▸ NPC1 O15118 3/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ VHL P40337 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22263324 0.99 AR (0.66) ARRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL30938129 0.99 AR (0.66) ARRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL26459201 0.93 AR (0.67) ARRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL26458268 0.90 AR (0.69) ARRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL26458194 0.89 AR (0.60) ARRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL22263288 0.89 AR (0.72) ARRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL22402900 0.88 AR (0.59) ARRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL22263246 0.88 AR (0.64) ARRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL26458197 0.86 AR (0.75) ARRAB9ANPC1SMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL30219487 0.85 AR (0.74) ARRAB9ANPC1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132823-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR DBD THERAPEUTICS, LLC 2023-05-04 — — US disclosed
US-20230132823-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR DBD THERAPEUTICS, LLC 2023-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230132823-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR AR, ADRM1, PSMA3 AR 1/4885RAB9A 3327/4885NPC1 3776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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