SCHEMBL26458348

SCHEMBL26458348

CCc1ccc(CC)c(I)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.43
CYP2A6 P11509 2/20 0.41
CYP1A2 P05177 1/20 0.41
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA2 P00918 1/20 0.35
TP53 P04637 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
BACE1 P56817 1/20 0.34
KIF11 P52732 1/20 0.34
AKR1C3 P42330 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15308135 0.87 PLK1 (0.37) TRPA1CYP2A6ALDH1A1LMNASMN1; SMN2
SCHEMBL24467914 0.81 TRPA1 (0.43) TRPA1CYP2A6CYP1A2ALDH1A1NPC1
SCHEMBL10274472 0.80 TRPA1 (0.46) TRPA1CYP2A6CYP1A2ALDH1A1NPC1
SCHEMBL29661799 0.80 TRPA1 (0.46) TRPA1CYP2A6CYP1A2ALDH1A1NPC1
SCHEMBL28274771 0.78 FOLH1 (0.42) MAPTL3MBTL1AKR1C3AKR1C2POLB
SCHEMBL13019662 0.78 TTR (0.36)
SCHEMBL444673 0.77 TRPA1 (0.48) TRPA1CYP2A6CYP1A2ALDH1A1NPC1
SCHEMBL8384809 0.76 TRPA1 (0.43) TRPA1CYP2A6CYP1A2ALDH1A1NPC1
SCHEMBL14102324 0.76 S1PR1 (0.46) TRPA1CYP2A6CYP1A2ALDH1A1NPC1
SCHEMBL16526930 0.76 MAPT (0.39) CYP2A6CYP1A2MAPTSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023074169-A1 PRIMER LAYER-FORMING COMPOSITION, LAMINATE, AND METHOD FOR DECOMPOSING LAMINATE 日産化学株式会社 2023-05-04 WO disclosed