Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216178 | 0.86 | ALDH1A1 (0.31) | SMN1; SMN2 | |
| SCHEMBL12076820 | 0.84 | TSHR (0.42) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL13786725 | 0.81 | — | — | |
| SCHEMBL37167 | 0.80 | ALDH1A1 (0.46) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL25476882 | 0.80 | TSHR (0.35) | TSHRMAPTKDM4ETDP1LMNA | |
| SCHEMBL25476884 | 0.79 | ALDH1A1 (0.31) | SMN1; SMN2 | |
| SCHEMBL9189882 | 0.77 | TSHR (0.34) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL13786724 | 0.76 | TSHR (0.35) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL10591032 | 0.76 | TSHR (0.44) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL10457681 | 0.76 | TSHR (0.39) | TSHRUSP2MAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133960-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2012-03-13 | — | — | US | disclosed |
| US-8133960-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2012-03-13 | — | — | US | disclosed |
| US-20100317817-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100317817-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |