Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.64 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.64 |
| ▸ | NSD2 | O96028 | 13/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.46 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30494449 | 1.00 | CYP11B1 (0.64) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL30494187 | 0.90 | NR3C2 (0.55) | CYP11B1CYP11B2PDE3BPDE3AMMP12 | |
| SCHEMBL26463277 | 0.90 | NR3C2 (0.55) | CYP11B1CYP11B2PDE3BPDE3AMMP12 | |
| SCHEMBL26463637 | 0.88 | CYP11B1 (0.49) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL30494352 | 0.88 | CYP11B1 (0.49) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL30494337 | 0.81 | GRIA1 (0.48) | CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL26463628 | 0.81 | GRIA1 (0.48) | CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL16475232 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL1119431 | 0.78 | CYP11B1 (1.00) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL30494335 | 0.78 | CYP11B1 (0.45) | CYP11B1CYP11B2PDE3BPDE3ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118176181-A | SARM1 modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-06-11 | — | — | CN | disclosed |
| WO-2023072026-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-05-04 | — | — | WO | disclosed |