Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.48 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 12/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26463628 | 1.00 | GRIA1 (0.48) | GRIA1CACNG8PDE3BPDE3ACYP11B1 | |
| SCHEMBL26463255 | 0.85 | GRIA1 (0.67) | GRIA1CACNG8PDE3BPDE3ACYP11B1 | |
| SCHEMBL29849879 | 0.85 | GRIA1 (0.67) | GRIA1CACNG8PDE3BPDE3ACYP11B1 | |
| SCHEMBL26463429 | 0.84 | CYP11B1 (0.64) | GRIA1CACNG8PDE3BPDE3ACYP11B1 | |
| SCHEMBL30494231 | 0.84 | CYP11B1 (0.64) | GRIA1CACNG8PDE3BPDE3ACYP11B1 | |
| SCHEMBL26463265 | 0.81 | CYP11B1 (0.64) | PDE3BPDE3ACYP11B1CYP11B2 | |
| SCHEMBL30494449 | 0.81 | CYP11B1 (0.64) | PDE3BPDE3ACYP11B1CYP11B2 | |
| SCHEMBL30494187 | 0.79 | NR3C2 (0.55) | PDE3BPDE3ACYP11B1CYP11B2 | |
| SCHEMBL26463277 | 0.79 | NR3C2 (0.55) | PDE3BPDE3ACYP11B1CYP11B2 | |
| SCHEMBL26463267 | 0.79 | CYP11B1 (0.62) | GRIA1CACNG8PDE3BPDE3ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236613-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2025-07-24 | — | — | US | disclosed |
| EP-4423067-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023072026-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250236613-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | SARM1, ADRM1, SMN1; SMN2 | GRIA1 256/4885CACNG8 1013/4885PDE3B 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.