⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18032673 | 0.57 | — | — | |
| SCHEMBL24595463 | 0.56 | TRPA1 (0.36) | — | |
| SCHEMBL29861109 | 0.54 | — | — | |
| Hydrochloric Acid SCHEMBL29459702 | 0.53 | TRPA1 (0.43) | — | |
| SCHEMBL29940088 | 0.53 | TRPA1 (0.43) | — | |
| Iodide SCHEMBL29564978 | 0.53 | TRPA1 (0.43) | — | |
| Ammonia Solution, Strong SCHEMBL23326973 | 0.53 | TRPA1 (0.43) | — | |
| Iodide SCHEMBL16149430 | 0.53 | TRPA1 (0.43) | — | |
| SCHEMBL29941648 | 0.53 | FYN (0.36) | — | |
| Bromide SCHEMBL30099792 | 0.53 | TRPA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4173675-A1 | IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 | Perha Pharmaceuticals (FR) | 2023-05-03 | — | — | EP | disclosed |