Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 10/20 | 0.92 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26498849 | 0.96 | CACNA1H (1.00) | CACNA1HALDH1A1KDM4EKMT2AEPHX1 | |
| SCHEMBL26499136 | 0.86 | CACNA1H (0.81) | CACNA1HALDH1A1KDM4EKMT2A | |
| SCHEMBL26082301 | 0.84 | CACNA1H (0.77) | CACNA1HALDH1A1KDM4EKMT2AEPHX1 | |
| SCHEMBL4365559 | 0.83 | ALDH1A1 (0.94) | CACNA1HALDH1A1KDM4EKMT2AEPHX1 | |
| SCHEMBL26463219 | 0.82 | CACNA1H (0.74) | CACNA1HALDH1A1KDM4EKMT2AEPHX1 | |
| SCHEMBL26082692 | 0.82 | CACNA1H (0.74) | CACNA1HALDH1A1KDM4EKMT2AEPHX1 | |
| SCHEMBL26082825 | 0.82 | CACNA1H (0.73) | CACNA1HALDH1A1KDM4EKMT2AEPHX1 | |
| SCHEMBL4216881 | 0.82 | ALDH1A1 (0.70) | CACNA1HALDH1A1KDM4EEPHX1POLB | |
| SCHEMBL26465830 | 0.81 | CACNA1H (0.73) | CACNA1HALDH1A1KDM4EKMT2APSMB5 | |
| SCHEMBL26463801 | 0.80 | CACNA1H (0.71) | CACNA1HALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |