Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2646449 | 1.00 | GCGR (1.00) | GCGRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL7229343 | 0.92 | GCGR (0.85) | GCGRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL2647970 | 0.92 | GCGR (0.85) | GCGRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL7229348 | 0.92 | GCGR (0.85) | GCGRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL2647968 | 0.92 | GCGR (0.85) | GCGRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL2646532 | 0.91 | GCGR (0.83) | GCGRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL2646533 | 0.91 | GCGR (0.83) | GCGRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL2646990 | 0.89 | GCGR (0.80) | GCGRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL2646988 | 0.89 | GCGR (0.80) | GCGRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL2647412 | 0.88 | GCGR (0.79) | GCGRMAPTKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | claimed |
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | disclosed |