Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 15/20 | 0.83 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2646533 | 1.00 | GCGR (0.83) | GCGRMAPTALDH1A1HPGDRAB9A | |
| SCHEMBL2646445 | 0.91 | GCGR (1.00) | GCGRMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL2646449 | 0.91 | GCGR (1.00) | GCGRMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL2647970 | 0.89 | GCGR (0.85) | GCGRMAPTALDH1A1HPGDRAB9A | |
| SCHEMBL2647968 | 0.89 | GCGR (0.85) | GCGRMAPTALDH1A1HPGDRAB9A | |
| SCHEMBL9071651 | 0.88 | GCGR (0.64) | GCGRMAPTALDH1A1HPGDRAB9A | |
| SCHEMBL7228347 | 0.88 | GCGR (0.69) | GCGRMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL7228351 | 0.88 | GCGR (0.69) | GCGRMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL2647316 | 0.86 | GCGR (1.00) | GCGRALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL2647315 | 0.86 | GCGR (1.00) | GCGRALDH1A1HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | claimed |
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | disclosed |