SCHEMBL26464626

SCHEMBL26464626

Cc1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc5c6c(cccc46)C=C5)cc3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.35
COMT P21964 1/20 0.34
CKS1B P61024 1/20 0.32
SKP2 Q13309 1/20 0.32
CRHR1 P34998 2/20 0.32
HPGD P15428 2/20 0.32
KDM4E B2RXH2 2/20 0.32
PPARG P37231 2/20 0.32
NCOA2 Q15596 1/20 0.32
NCOA1 Q15788 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
RAB9A P51151 3/20 0.31
NPC1 O15118 2/20 0.31
NTSR1 P30989 1/20 0.31
POLB P06746 2/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22338423 0.94 KDM4E (0.32) KDM4EL3MBTL1RAB9ATDP1CYP2C19
SCHEMBL22338447 0.94 KDM4E (0.32) KDM4EL3MBTL1RAB9ATDP1CYP2C19
SCHEMBL22338443 0.86 PIK3CA (0.30)
SCHEMBL22338505 0.86 PIK3CA (0.30)
SCHEMBL26464635 0.85
SCHEMBL22338496 0.82 RXRA (0.33)
SCHEMBL5034594 0.82 PARP1 (0.38) HPGDKDM4ERAB9ASMN1; SMN2MEN1
SCHEMBL401706 0.81 CYP1A2 (0.42) HPRT1COMTCKS1BSKP2HPGD
SCHEMBL10041934 0.81 CYP1A2 (0.42) HPRT1COMTCKS1BSKP2HPGD
SCHEMBL13900009 0.81 COMT (0.40) COMTCRHR1HPGDKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022733-B2 Organic electroluminescence device and monoamine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-25 US disclosed
US-20230137318-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-04 US disclosed