Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808636 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNASLC6A5SMN1; SMN2 | |
| SCHEMBL29803356 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNASLC6A5SMN1; SMN2 | |
| SCHEMBL10036437 | 0.89 | MAPT (0.55) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL574624 | 0.88 | MAPT (0.49) | ALDH1A1MAPTLMNASLC6A5DRD2 | |
| SCHEMBL574625 | 0.88 | MAPT (0.49) | ALDH1A1MAPTLMNASLC6A5DRD2 | |
| SCHEMBL30425302 | 0.87 | MAPT (0.55) | ALDH1A1MAPTLMNASLC6A5MAPK1 | |
| SCHEMBL26495535 | 0.87 | MAPT (0.55) | ALDH1A1MAPTLMNASLC6A5MAPK1 | |
| SCHEMBL15244150 | 0.86 | MAPT (0.44) | ALDH1A1MAPTLMNASLC6A5DRD2 | |
| SCHEMBL10126924 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL25194818 | 0.84 | KDM4E (0.46) | ALDH1A1MAPTMAPK1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339936-A1 | COMPOUND HAVING KINASE INHIBITORY ACTIVITY | CYTOSINLAB THERAPEUTICS CO., LTD. (CN) | 2023-10-26 | — | — | US | disclosed |
| US-20230138863-A1 | SUBSTITUTED DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND AND A COMPOSITION CONTAINING THE COMPOUND AND USE THEREOF | SHENZHEN TARGETRX, INC. (CN) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138863-A1 | SUBSTITUTED DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND AND A COMPOSITION CONTAINING THE COMPOUND AND USE THEREOF | FLT3, AXL, ABL1 | ALDH1A1 2607/4885MAPT 2354/4885LMNA 3768/4885 |
| US-20230339936-A1 | COMPOUND HAVING KINASE INHIBITORY ACTIVITY | FLT3, ERBB2, ABL1 | ALDH1A1 2716/4885MAPT 2898/4885LMNA 3233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.