SCHEMBL26465252

SCHEMBL26465252

Cc1ccc2c(c1)[nH]c1ccc(Br)cc12

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.64
CHUK O15111 1/20 0.53
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.50
ACHE P22303 2/20 0.46
PIM3 Q86V86 1/20 0.45
RXFP1 Q9HBX9 1/20 0.44
MAPK1 P28482 1/20 0.44
AR P10275 1/20 0.44
MEN1 O00255 2/20 0.43
NPC1 O15118 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20327619 0.93 KIF11 (0.59) KIF11CHUKLMNAHPGDACHE
SCHEMBL6979361 0.90 KIF11 (0.55) KIF11CHUKLMNAHPGDACHE
SCHEMBL6007682 0.90 KIF11 (0.62) KIF11LMNAHPGDPIM3RXFP1
SCHEMBL10141055 0.86 KIF11 (0.75) KIF11LMNAHPGDACHERXFP1
SCHEMBL16552984 0.86 CHUK (0.61) KIF11CHUKLMNAHPGDPIM3
SCHEMBL29726991 0.86 KIF11 (0.75) KIF11LMNAHPGDACHERXFP1
SCHEMBL29764121 0.86 CHUK (0.61) KIF11CHUKLMNAHPGDPIM3
SCHEMBL13828017 0.82 KIF11 (0.72) KIF11LMNAACHEPIM3RXFP1
SCHEMBL18830699 0.82 CHUK (0.60) CHUKLMNAHPGDPIM3RXFP1
SCHEMBL29366993 0.82 CHUK (0.64) CHUKLMNAHPGDPIM3RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807654-B2 Organometallic compound, organic light-emitting device including organometallic compound, and diagnostic composition including organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-07 US disclosed
US-20230138421-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230138421-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD2, OCIAD1, OXER1 KIF11 2834/4885CHUK 4188/4885LMNA 4732/4885
US-11807654-B2 Organometallic compound, organic light-emitting device including organometallic compound, and diagnostic composition including organometallic compound L1CAM, FOXM1, MEN1 KIF11 487/4885CHUK 3216/4885LMNA 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.