Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10280096 | 0.86 | BRD4 (0.53) | BRD4LTA4HSMN1; SMN2 | |
| SCHEMBL13189158 | 0.83 | BRD4 (0.50) | BRD4LTA4HSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22698530 | 0.83 | BRD4 (0.49) | BRD4TSHRLTA4HSMN1; SMN2GAA | |
| SCHEMBL2864044 | 0.79 | BRD4 (0.50) | BRD4LTA4HSMN1; SMN2 | |
| SCHEMBL15285886 | 0.79 | BRD4 (0.50) | BRD4TSHRLTA4HGAAHSD17B10 | |
| SCHEMBL23197908 | 0.79 | BRD4 (0.50) | BRD4TSHRLTA4HSMN1; SMN2GAA | |
| SCHEMBL19051290 | 0.79 | BRD4 (0.46) | BRD4TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL25678365 | 0.79 | MGAM (0.43) | BRD4TSHRGAAHSD17B10MGAM | |
| SCHEMBL2911131 | 0.79 | BRD4 (0.46) | BRD4LTA4HSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2911129 | 0.79 | BRD4 (0.46) | BRD4LTA4HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072257-A1 | PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-04 | — | — | WO | disclosed |