Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465285 | 0.83 | BRD4 (0.58) | BRD4TSHRSMN1; SMN2HSD17B10MGAM | |
| SCHEMBL22698528 | 0.81 | BRD4 (0.43) | BRD4TSHRSMN1; SMN2HSD17B10MGAM | |
| SCHEMBL19051290 | 0.79 | BRD4 (0.46) | BRD4TSHRSMN1; SMN2 | |
| SCHEMBL5638542 | 0.77 | TSHR (0.46) | BRD4TSHRHSD17B10MGAMGAA | |
| SCHEMBL5638546 | 0.77 | TSHR (0.46) | BRD4TSHRHSD17B10MGAMGAA | |
| SCHEMBL14499820 | 0.77 | TSHR (0.46) | BRD4TSHRHSD17B10MGAMGAA | |
| SCHEMBL22698529 | 0.75 | SLC6A12 (0.46) | TSHR | |
| SCHEMBL18629609 | 0.75 | SLC6A12 (0.46) | TSHR | |
| SCHEMBL10280096 | 0.74 | BRD4 (0.53) | BRD4SMN1; SMN2LTA4H | |
| SCHEMBL1863234 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020234636-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF MAMMALIAN INFECTIONS | CADILA HEALTHCARE LIMITED (IN) | 2020-11-26 | — | — | WO | disclosed |