⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30028795 | 1.00 | — | — | |
| SCHEMBL11515398 | 0.93 | TRPA1 (0.52) | — | |
| Cyanate SCHEMBL11865647 | 0.89 | TRPA1 (0.48) | — | |
| SCHEMBL2122383 | 0.79 | — | — | |
| SCHEMBL6517277 | 0.77 | TRPA1 (0.56) | — | |
| SCHEMBL6516427 | 0.77 | TRPA1 (0.56) | — | |
| SCHEMBL6517281 | 0.77 | TRPA1 (0.56) | — | |
| SCHEMBL29373274 | 0.75 | — | — | |
| SCHEMBL331198 | 0.75 | — | — | |
| SCHEMBL29406334 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758488-B2 | Method for preparing phenyloxymethyl-nitro-imidazole derivatives and use of same | SANOFI (FR) | 2017-09-12 | — | — | US | claimed |
| EP-2922822-B1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | SANOFI SA (FR) | 2016-12-28 | — | — | EP | claimed |
| US-20150291536-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | SANOFI (FR) | 2015-10-15 | — | — | US | claimed |
| EP-2922822-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | Sanofi (FR) | 2015-09-30 | — | — | EP | claimed |
| WO-2014079497-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | DRUGS FOR NEGLECTED DISEASES INITIATIVE (DNDI) (CH) | 2014-05-30 | — | — | WO | claimed |
| EP-2913302-B1 | CYANOGEN-HALIDE PRODUCTION METHOD, CYANATE ESTER COMPOUND AND PRODUCTION METHOD THEREFOR, AND RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2019-04-10 | — | — | EP | disclosed |
| CN-107709288-A | Phosphamide derivative and preparation method and application thereof | 四川海思科制药有限公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-104797562-B | The preparation method and its usage of phenoxymethyl nitro imidazole derivatives | 赛诺菲 | 2017-10-03 | — | — | CN | disclosed |
| US-9758488-B2 | Method for preparing phenyloxymethyl-nitro-imidazole derivatives and use of same | SANOFI (FR) | 2017-09-12 | — | — | US | disclosed |
| US-9758488-B2 | Method for preparing phenyloxymethyl-nitro-imidazole derivatives and use of same | SANOFI (FR) | 2017-09-12 | — | — | US | disclosed |
| US-9581501-B2 | Temperature control material | NIGK CORPORATION (JP) | 2017-02-28 | — | — | US | disclosed |
| EP-2922822-B1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | SANOFI SA (FR) | 2016-12-28 | — | — | EP | disclosed |
| US-4067972-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4042705-A | 1-Methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |
| US-4027018-A | INSECTICIDES, ACARACIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-4013794-A | O-ALKYL-S-ALKYL-O-PHENYL PHOSPHATES AND INSECTICIDAL AND ACARICIDAL METHOD OF USE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-4013795-A | INSECTICIDE, MITICIDE, NEMATOCIDE, FUNGICIDE, BACTERICIDE, RODENTICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-4000270-A | INSECTIDES, ACARICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3994949-A | REACTION OF PHENOLATE WITH CYANOGEN HALIDE, TERT-AMINE CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |
| US-3954919-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |