SCHEMBL26465858

SCHEMBL26465858

Cc1ccc2c3ccccc3c3cc(I)ccc3c2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.44
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
MAOA P21397 1/20 0.39
CYP2A6 P11509 4/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP1A2 P05177 5/20 0.38
HPRT1 P00492 1/20 0.36
PGR P06401 1/20 0.35
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
RORB Q92753 1/20 0.35
ACHE P22303 1/20 0.35
NQO2 P16083 1/20 0.34
LMNA P02545 3/20 0.34
MAPT P10636 2/20 0.34
GAA P10253 1/20 0.34
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22594660 1.00 KIF11 (0.44) KIF11MEN1NPC1POLBKMT2A
SCHEMBL29617337 0.86 HPRT1 (0.41) CYP2A6TDP1CYP1A2HPRT1ALDH1A1
SCHEMBL17180585 0.86 KIF11 (0.54) KIF11MEN1NPC1POLBKMT2A
SCHEMBL19336421 0.86 HPRT1 (0.41) CYP2A6TDP1CYP1A2HPRT1ALDH1A1
SCHEMBL8840916 0.86 KIF11 (0.54) KIF11MEN1NPC1POLBKMT2A
SCHEMBL12741708 0.86 HPRT1 (0.41) CYP2A6TDP1CYP1A2HPRT1ALDH1A1
SCHEMBL3873030 0.78 CYP1A2 (0.50) KIF11CYP2A6TDP1CYP1A2ACHE
SCHEMBL8840917 0.78 CYP1A2 (0.50) KIF11CYP2A6TDP1CYP1A2ACHE
SCHEMBL20961501 0.78 CYP1A2 (0.39) KIF11MEN1KMT2AMAOACYP2A6
SCHEMBL23618575 0.77 CYP1A2 (0.50) MEN1NPC1POLBKMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4174060-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-05-03 EP disclosed