Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22856067 | 1.00 | HRH3 (0.37) | HRH3CCR2KCNH2DRD3PIK3CD | |
| SCHEMBL22848948 | 1.00 | HRH3 (0.37) | HRH3CCR2KCNH2DRD3PIK3CD | |
| SCHEMBL21106666 | 0.88 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL22837733 | 0.88 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL24379841 | 0.88 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL24509130 | 0.87 | — | — | |
| SCHEMBL23559954 | 0.86 | EPHA2 (0.33) | DRD3 | |
| SCHEMBL22856341 | 0.86 | EPHA2 (0.33) | DRD3 | |
| SCHEMBL22837759 | 0.85 | GBA1 (0.33) | — | |
| SCHEMBL22837765 | 0.85 | GBA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192578-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023077077-A1 | RNA DEGRADERS AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |