Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320336 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL28320369 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL21494402 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL25091044 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL10677633 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL25069142 | 1.00 | EPHX1 (0.58) | EPHX1ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL29156205 | 0.98 | EPHX1 (0.55) | EPHX1ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL23710267 | 0.93 | EPHX1 (0.47) | EPHX1ALDH1A1GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL28608172 | 0.91 | EPHX1 (0.46) | EPHX1ALDH1A1GNAI3GNAO1GNAI1 | |
| Iodide SCHEMBL28167228 | 0.91 | EPHX1 (0.46) | EPHX1ALDH1A1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135560-A1 | GEM-DISUBSTITUTED PIPERIDINE MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135560-A1 | GEM-DISUBSTITUTED PIPERIDINE MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | MC1R, MC3R, MC2R | EPHX1 3918/4885ALDH1A1 2971/4885GNAI3 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.