Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 3/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26833953 | 0.96 | ESR1 (0.44) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL25811140 | 0.95 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL26465653 | 0.94 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL26465659 | 0.92 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL26833978 | 0.91 | ESR1 (0.49) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL23667865 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL26465657 | 0.89 | MAPT (0.47) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL26465658 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL25811178 | 0.87 | GPR119 (0.47) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL26465029 | 0.87 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023071073-A1 | ARYLAMINE ORGANIC COMPOUND AND USE THEREOF | 广州华睿光电材料有限公司 | 2023-05-04 | — | — | WO | disclosed |