Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2664502 | 0.85 | EPHX2 (0.52) | EPHX2FABP5KMT2ACASP3ABL1 | |
| SCHEMBL569486 | 0.81 | EPHX2 (0.60) | EPHX2FABP5KMT2ASMN1; SMN2CASP3 | |
| SCHEMBL2650528 | 0.79 | EPHX2 (0.51) | EPHX2FABP5KMT2ASMN1; SMN2CASP3 | |
| SCHEMBL2744941 | 0.79 | EPHX2 (0.62) | EPHX2FABP5KMT2ACASP3 | |
| SCHEMBL9472298 | 0.79 | ALDH1A1 (0.57) | KMT2ASMN1; SMN2POLBMEN1 | |
| SCHEMBL2744944 | 0.78 | EPHX2 (0.72) | EPHX2FABP5KMT2ACASP3 | |
| SCHEMBL2649418 | 0.78 | EPHX2 (0.50) | EPHX2FABP5KMT2ASMN1; SMN2CASP3 | |
| SCHEMBL29972110 | 0.78 | EPHX2 (0.53) | EPHX2FABP5KMT2ASMN1; SMN2CASP3 | |
| SCHEMBL27081620 | 0.78 | EPHX2 (0.53) | EPHX2FABP5KMT2ASMN1; SMN2CASP3 | |
| SCHEMBL8366871 | 0.76 | EPHX2 (0.64) | EPHX2KMT2ASMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |