Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29830272 | 0.88 | FGFR1 (0.62) | FGFR1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL2646728 | 0.81 | FGFR1 (0.69) | FGFR1ALDH1A1HPGDPOLBHTT | |
| SCHEMBL29449347 | 0.79 | FGFR1 (1.00) | FGFR1ALDH1A1HPGDHTTMAPT | |
| SCHEMBL2308773 | 0.79 | FGFR1 (1.00) | FGFR1ALDH1A1HPGDHTTMAPT | |
| SCHEMBL29830224 | 0.75 | PARP1 (0.49) | FGFR1ALDH1A1HPGDHTTEGLN1 | |
| SCHEMBL2646675 | 0.74 | FGFR1 (0.63) | FGFR1ALDH1A1HPGDPOLBMAPT | |
| SCHEMBL6803506 | 0.72 | FGFR1 (0.60) | FGFR1ALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL12191226 | 0.71 | SMN1; SMN2 (0.51) | FGFR1ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL6755687 | 0.70 | FGFR1 (0.58) | FGFR1ALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL9163594 | 0.70 | FGFR1 (0.53) | FGFR1ALDH1A1HPGDSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0616807-B1 | Benzimidazole useful in the treatment of central nervous system disorders | NEUROSEARCH AS (DK) | 1998-07-08 | — | — | EP | disclosed |
| US-5554632-A | CENTRAL NERVOUS SYSTEM | NEUROSEARCH A/S (DK) | 1996-09-10 | — | — | US | disclosed |
| US-5554630-A | TREATING ANXIETY, CONVULSIONS AND SLEEP DISORDERS IN LIVING ANIMALS BY MODULATION OF THE BENZODIAZEPINE RECEPTOR OF THE CENTRAL NERVOUS SYSTEM WITH 1-/3-HETEROCYCLYLPHENYL/-BENZIMIDAZOLES | NEUROSEARCH A/S (DK) | 1996-09-10 | — | — | US | disclosed |
| EP-0616807-A1 | Benzimidazole useful in the treatment of central nervous system disorders | NEUROSEARCH A/S (DK) | 1994-09-28 | — | — | EP | disclosed |