Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29449347 | 1.00 | FGFR1 (1.00) | FGFR1ALDH1A1HPGDHTTMAPT | |
| SCHEMBL3834819 | 0.84 | FGFR1 (0.72) | FGFR1ALDH1A1HPGDHTTMAPT | |
| SCHEMBL2646728 | 0.82 | FGFR1 (0.69) | FGFR1ALDH1A1HPGDHTTMAPT | |
| SCHEMBL19911376 | 0.81 | FGFR1 (1.00) | FGFR1ALDH1A1HPGDHTTMAPT | |
| SCHEMBL3342620 | 0.81 | ALDH1A1 (1.00) | FGFR1ALDH1A1HPGDHTTMAPT | |
| SCHEMBL3417304 | 0.81 | HTT (0.78) | FGFR1HTT | |
| SCHEMBL2647103 | 0.79 | FGFR1 (0.65) | FGFR1ALDH1A1HPGDHTTMAPT | |
| SCHEMBL2646675 | 0.78 | FGFR1 (0.63) | FGFR1ALDH1A1HPGDMAPT | |
| SCHEMBL29830083 | 0.77 | FGFR1 (1.00) | FGFR1ALDH1A1HPGDHTT | |
| SCHEMBL27241663 | 0.77 | FGFR1 (1.00) | FGFR1ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133404-A | Preparation method and application of copper-based coordination polymer with mixed valence states | 洛阳师范学院 | 2022-03-04 | — | — | CN | claimed |
| CN-114133404-A | Preparation method and application of copper-based coordination polymer with mixed valence states | 洛阳师范学院 | 2022-03-04 | — | — | CN | disclosed |
| EP-2348855-A2 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | Burnham Institute for Medical Research (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010033643-A2 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-03-25 | — | — | WO | disclosed |
| US-6218388-B1 | THERAPY OF PROTEIN TYROSINE KINASE MEDIATED CANCER, ATHEROSCLEROSIS, RESTENOSIS, AND PSORIASIS BY ADMINISTERING BENZIMIDAZOLE DERIVATIVE | WARNER-LAMBERT COMPANY | 2001-04-17 | — | — | US | disclosed |
| US-5990146-A | TREATING PROTEIN TYROSINE KINASE MEDIATED CANCER; ANTICARCINOGENIC AGENTS; ATHEROSCLEROSIS; RESTENOSIS; PSORIASIS; ANTIPROLIFERATIVE AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-11-23 | — | — | US | disclosed |