SCHEMBL26472425

SCHEMBL26472425

c1ccc(-n2c3ccccc3c3c(-n4c5ccccc5c5cc(-n6c7ccccc7c7c6ccc6c8ccccc8n(-c8ccccc8)c67)ccc54)cccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 2/20 0.35
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
KDR P35968 1/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
BRCA1 P38398 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
PTPN1 P18031 2/20 0.30
PPARG P37231 1/20 0.30
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26472363 1.00 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL24531878 1.00 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL26472434 1.00 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL26472359 0.97 KDM4E (0.49) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL26472589 0.96 KDM4E (0.47) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL26472431 0.95 L3MBTL1 (0.42) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL26472401 0.95 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL23600661 0.95 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL26809577 0.95 KDM4E (0.49) KDM4EATML3MBTL1ALDH1A1JAK2
SCHEMBL26899209 0.95 KDM4E (0.49) KDM4EATML3MBTL1ALDH1A1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230136708-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230136708-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed