Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10757117 | 0.91 | EPAS1 (0.32) | EPAS1 | |
| SCHEMBL8603606 | 0.85 | EPAS1 (0.34) | EPAS1 | |
| SCHEMBL22460801 | 0.84 | EPAS1 (0.32) | EPAS1 | |
| SCHEMBL17881911 | 0.83 | EPAS1 (0.32) | EPAS1 | |
| SCHEMBL2292798 | 0.82 | — | — | |
| SCHEMBL21722414 | 0.77 | — | — | |
| SCHEMBL10914129 | 0.77 | — | — | |
| SCHEMBL8901938 | 0.76 | CHRNB2 (0.30) | — | |
| SCHEMBL9726321 | 0.72 | EPAS1 (0.31) | EPAS1 | |
| SCHEMBL1434651 | 0.72 | EPAS1 (0.31) | EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463715-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |
| EP-1124830-A1 | PYRIMIDIN-4-ENAMINE AS FUNGICIDE | Syngenta Participations AG (CH) | 2001-08-22 | — | — | EP | disclosed |
| EP-1087939-A1 | PROCESS FOR PREPARATION OF PYRIMIDINONE DERIVATIVES | Syngenta Participations AG (CH) | 2001-04-04 | — | — | EP | disclosed |
| EP-1015434-A2 | NOVEL PYRIMIDIN-4-ONE AND PYRIMIDIN-4-THIONE AS FUNGICIDE | Novartis AG (CH) | 2000-07-05 | — | — | EP | disclosed |
| EP-1015435-A1 | PYRIMIDIN-2-OXY-4-ONE AND PYRIMIDIN-2-OXY-4-THIONE DERIVATIVES | Novartis AG (CH) | 2000-07-05 | — | — | EP | disclosed |
| WO-2000031082-A1 | PYRIMIDIN-4-ENAMINE AS FUNGICIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2000-06-02 | — | — | WO | disclosed |
| EP-0993432-A1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL ACETOPHENONE | Novartis AG (CH) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999067202-A1 | PROCESS FOR PREPARATION OF PYRIMIDINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG . (CH) | 1999-12-29 | — | — | WO | disclosed |
| EP-0912499-A1 | PESTICIDES | Novartis AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1999014202-A2 | NOVEL PYRIMIDIN-4-ONE AND PYRIMIDIN-4-THIONE AS FUNGICIDE | NOVARTIS AG (CH) | 1999-03-25 | — | — | WO | disclosed |
| WO-1999011631-A1 | PYRIMIDIN-2-OXY-4-ONE AND PYRIMIDIN-2-OXY-4-THIONE DERIVATIVES | NOVARTIS AG (CH) | 1999-03-11 | — | — | WO | disclosed |
| EP-0888359-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | Novartis AG (CH) | 1999-01-07 | — | — | EP | disclosed |
| WO-1998058895-A1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL ACETOPHENONE | NOVARTIS AG (CH) | 1998-12-30 | — | — | WO | disclosed |
| WO-1997047592-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-12-18 | — | — | WO | disclosed |
| WO-1997033890-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | NOVARTIS AG (CH) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997014688-A1 | A PROCESS FOR THE PREPARATION OF α-CHLOROMETHYLPHENYLACETIC ACID DERIVATIVES | NOVARTIS AG (CH) | 1997-04-24 | — | — | WO | disclosed |