Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26473067 | 0.95 | MAPT (0.51) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT | |
| SCHEMBL26473085 | 0.93 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT | |
| SCHEMBL23326169 | 0.89 | MKNK1 (0.56) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT | |
| SCHEMBL29775379 | 0.89 | MKNK1 (0.56) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT | |
| SCHEMBL26473195 | 0.88 | PDE10A (0.48) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT | |
| SCHEMBL29775344 | 0.85 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT | |
| SCHEMBL23326295 | 0.85 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT | |
| SCHEMBL23326124 | 0.83 | MKNK1 (0.51) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT | |
| SCHEMBL23326242 | 0.82 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT | |
| SCHEMBL29775399 | 0.82 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11642336-B2 | 5-HT2A agonists for use in treatment of depression | Lophora ApS (DK) | 2023-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11642336-B2 | 5-HT2A agonists for use in treatment of depression | HTR2A, HTR2C, HTR5A | CYP11B1 1886/4885CYP11B2 855/4885CYP19A1 894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.