Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662559 | 0.93 | GCGR (1.00) | GCGRMAPK14 | |
| SCHEMBL12486404 | 0.91 | GCGR (0.83) | GCGRMAPK14 | |
| SCHEMBL8322278 | 0.87 | GCGR (0.77) | GCGRMAPK14 | |
| SCHEMBL2648304 | 0.87 | GCGR (0.76) | GCGRMAPK14 | |
| SCHEMBL6586611 | 0.86 | GCGR (0.86) | GCGRMAPK14 | |
| SCHEMBL8680959 | 0.85 | GCGR (0.79) | GCGRMAPK14 | |
| SCHEMBL2647609 | 0.82 | GCGR (0.79) | GCGRMAPK14 | |
| SCHEMBL21557189 | 0.82 | GCGR (1.00) | GCGRMAPK14 | |
| SCHEMBL2646022 | 0.82 | GCGR (0.71) | GCGRMAPK14 | |
| SCHEMBL5107178 | 0.81 | GCGR (0.76) | GCGRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859771-A4 | SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2000-03-15 | — | — | EP | claimed |
| EP-0859771-A1 | SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 1998-08-26 | — | — | EP | claimed |
| US-5776954-A | GLUCAGON ANTAGONISTS | MERCK & CO., INC. (US) | 1998-07-07 | — | — | US | claimed |
| WO-1997016442-A1 | SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | claimed |